Basal cell carcinoma (BCC) develops in the basal cell layer of the epidermis and, like most skin cancers, is caused by long-term or excessive exposure to the sun.1Consequently, BCC is most often found on the head and neck, and other sun exposed areas.2
While the majority of people with BCC are fair skinned or have skin that does not tan very easily, anyone can be at risk.1 Individuals who develop BCC are at a greater risk of developing further BCCs:2 research suggests the risk is up to 15 times greater than the average risk of developing skin cancer.3 Individuals with a melanoma have a three to five times higher than average risk of developing a non-melanoma skin cancer.3 BCC also presents more often in men than women.4Other risk factors include:2,5
- A genetic predisposition
- Sun exposure as a child
- Increasing age
- UV radiation (UVR)
- A high dietary fat intake
1. Weedon D, et al. Keratinocytic tumours. In: LeBoit PE, Burg G, Weedon D, Sarasain A, eds. WHO classification of tumours. Pathology and genetics of skin tumours. IARC Press: Lyon 2006.
2. Maloney et al. Pigmented basal cell carcinoma: Investigation of 70 cases. J Am Acad Dermatol. 1992;27(1):74-8.3. Wong B, et al. Basal Cell Carcinoma. BMJ. 2003;327:794-798.